Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib
Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo | PNAS
Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer
Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer | Cell Death Discovery
Cancers | Free Full-Text | Targeting NEDDylation as a Novel Approach to Improve the Treatment of Head and Neck Cancer
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
Frontiers | Neddylation: A Versatile Pathway Takes on Chronic Liver Diseases
Anticancer drug discovery by targeting cullin neddylation - ScienceDirect
Frontiers | Advances in Cancer Treatment by Targeting the Neddylation Pathway
MLN4924 specifically inhibits neddylation and suppresses the growth of... | Download Scientific Diagram
Mechanism of MLN4924 action. Proposed mechanisms of how MLN4924... | Download Scientific Diagram
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells | Scientific Reports
Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells | Scientific Reports
Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic Investigation and Therapeutic Implication | Bentham Science
Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy | Cell Death Discovery
Celecoxib Synergistically Enhances MLN4924-Induced Cytotoxicity and EMT Inhibition Via AKT and ERK Pathways in Human Urothelial Carcinoma - Shida Xiong, Wei Huang, Xiaoqiang Liu, Qian Chen, Yi Ding, Haoxuan Huang, Ru Zhang,
The NAE inhibitor pevonedistat (MLN4924) synergizes with TNF-α to activate apoptosis | Cell Death Discovery
Neddylation regulation of mitochondrial structure and functions | Cell & Bioscience | Full Text
SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma | Journal of Experimental & Clinical Cancer Research | Full Text
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression
Schema of the mechanism for MLN4924 enhancing ATRA-induced... | Download Scientific Diagram
Continued ) F, schematic illustration of proposed mechanism underlying... | Download Scientific Diagram
The MLN4924 inhibitor exerts a neuroprotective effect against oxidative stress injury via Nrf2 protein accumulation - ScienceDirect
![PDF] The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/80cbd857543023682a105253c4bdb96a358339a4/4-Figure1-1.png "PDF] The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth. | Semantic Scholar")
PDF] The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth. | Semantic Scholar
Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis | Cell Death & Disease
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy
Figure 5 | Targeting the Neddylation Pathway to Suppress the Growth of Prostate Cancer Cells: Therapeutic Implication for the Men's Cancer
